Manager, Commercial Strategy Analytics

The Organization What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. Through proprietary and versatile approaches, Entrada is advancing a robust development portfolio of genetic medicines for the potential treatment of neuromuscular and inherited retinal diseases, among others. Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne muscular dystrophy (DMD) who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered with Vertex Pharmaceuticals to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1 (DM1). 2026 represents a catalyst-rich period for Entrada. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51). These programs are complemented by the ongoing clinical progress of our DM1 collaboration with Vertex (VX-670). We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. The Perfect Addition to Our Team You are interested in working at the intersection of life sciences and business. You want to join a high-growth biotech company in a business strategy role to support the team by synthesizing and communicating strategic insights as we prepare for commercial launch. You bring to the table a combination of an inquisitive spirit, critical thinking, and deep analytical skills and you love performing data-driven analyses to generate strategic insights. You are comfortable working in ambiguity and thrive in fast paced situations. You look forward to working with and learning from leaders across the organization in a high impact role. The Opportunity This position will report to the Director of Business Development and Corporate Strategy and support a variety of projects for the early commercial strategy team. Example workstreams include partnership and ownership across competitive intelligence, market research, and forecasting analysis. You’ll conduct primary and secondary market research to gather data to drive key insights and analyses to support Entrada’s pre-commercial strategy. You’ll be expected to be a key member of the team by distilling market insights and data in a timely fashion to generate strategic takeaways and recommendations for key decision makers across the organization. Responsibilities

Support development of asset-level and portfolio-level pre-commercial or commercial readiness analyses across target indications and geographies. Conduct market sizing, epidemiology, competitive landscape, and pricing & reimbursement analyses. Build and maintain revenue forecast models incorporating insights from the evolving clinical, regulatory, and market landscape. Support continued development of existing initiatives across the corporate strategy team. Gather and capture market data to support data-driven analyses, generate strategic insights, and communicate findings in an efficient manner.

The Necessities At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

Humanity - We genuinely care about patients and about one another. Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients. Creativity - We are creative problem solvers. Collaboration - We are more than the sum of our parts. Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

Bachelor’s degree in a life sciences discipline required; PhD, MBA or other advanced degree strongly preferred. 5+ years of relevant experience, preferably in an analytical role such as market research, equity research, life sciences consulting, commercial analytics, or prior experience in biotech/pharma. Direct experience synthesizing and communicating competitive insights from drug development programs and/or companies. Exceptional analytical skills combined with a broad understanding of the life sciences business and R&D process. Excellent communication skills engaging with external experts and internal stakeholders to gather insights and feedback. Experience building and interpreting financial models and communicating modeling outputs to support strategic decision making. Familiarity with the rare disease space and a desire to work in a fast-paced, innovative, and collaborative environment. Ability to be a team player with a can-do attitude and a willingness to embrace new challenges and the flexibility to adjust course, based on new findings and team inputs.

This is a hybrid position, with the requirement for candidates to be based out of Entrada Therapeutics headquarters office 2-3 days per week in Boston, MA.

What We Offer: Meaningful Work, Fair Rewards, and Real Support

At Entrada Therapeutics, we understand that compensation and total rewards are a major consideration when exploring a new opportunity. We believe in transparency and equity and are committed to sharing salary ranges for every position, along with insight into our compensation philosophy, in accordance with certain state requirements in the United States and fostering a fair and open environment at the onset. But we also know it is more than just pay. When you join Entrada, you’ll be part of a mission-driven team with access to comprehensive health, dental and vision coverage; life and disability insurance; with a 401(k) match. We pride ourselves on offering competitive benefits that empower